Multiple Myeloma Treatments
Below are links to information from the National Cancer Institute (NCI) about FDA-approved, commonly used medications for the treatment of multiple myeloma. NCI also has an extensive list of multiple myeloma meds, including many older drugs.
(Maybe the best feature is that the NCI site pronounces the name of the drug for you :) )
Alkylating Agents
Antibody Drug Conjugate
- Blenrep (belantamab mafodotin) Note: GSK pulls Blenrep from the US market on Nov. 22, 2022 due to DREAMM-3 clinical trial results
Bi-Specific T-Cell Engager
Bisphosphonates (to treat bone disease, not myeloma itself))
Cell-Based Gene Therapy
Corticosteroids
COVID-19 Treatment
- Evusheld (combination of tixagevimab and cilgavimab) (for COVID-19 prophylaxis/prevention)
- Paxlovid (nirmatrelvir and ritonavir)
NIH Information on Anti-SARS-CoV-2 Monoclonal Antibodies
Chromosome Region Maintenance 1 Protein (CRM1) Inhibitor
Histone Deacetylase (HDAC) Inhibitor
Immunomodulatory Agents
Monoclonal Antibodies
- Darzalex (daratumumab)
- Darzalex Faspro (daratumumab and hyaluronidase)
- Empliciti (elotuzumab)
- Sarclisa (isatuximab)
- Xgeva (denosumab) used in some cases to treat bone disease instead of bisphosphonates